L-Carnitina

[JaVlOrD]

bueno un amigo me recomendo que me comprara estas pastillas http://www.nutrimarket.cl/nutrigen/index.php?option=com_content&view=article&id=143%3Aultra-ripped&catid=35%3Aall-productos&Itemid=57 (ultra ripped y me dijo que eran para adelgazar mas rapido con ejercicio obiamente, pero queria saber cuando tomarlas :|, la cosa es que yo aparte de andar en bici hago rugby, enton c tendria que tomarmelas 1 hora antes de hacer rugby o salir a andar en bici, o tomarmelas en la mañana en el desayuno y el efecto durara todo el dia? o en el almuerzo? esa es mi consulta, gracias

[carlos]

1 cápsula en ayunas y 1 cápsula 30 minutos antes de realizar ejercicio.
De todas formas no esperes milagros...el mejor quema grasas es dieta y cardio.

[Frutos111]

1 cápsula en ayunas y 1 cápsula 30 minutos antes de realizar ejercicio.
De todas formas no esperes milagros...el mejor quema grasas es dieta y cardio.

[JaVlOrD]

1 cápsula en ayunas y 1 cápsula 30 minutos antes de realizar ejercicio.
De todas formas no esperes milagros...el mejor quema grasas es dieta y cardio.

no si obio si se, la verdad los fines de semana por lo general salgo a andar en bici unas 3 o 4 horas, y 1 dia a la semana hago fisico en rugby, otra cosa y disculpen mi ignorancia, en ayunas, osea me la tomo en la mañana antes de desayunar?

[carlos]

Si, en ayunas es sin tener nada reciente en el estomago

[raskolnikov]

En humanos esta demostrada su INEFICACIA como ayuda a la perdida de grasa.

[Manu B.]

En humanos esta demostrada su INEFICACIA como ayuda a la perdida de grasa.

¿Puedes poner el estudio o hacer referencia? no por que dude de tu palabra, pero es un tema que me interesa bastante. ¿Que recomiendas como ayuda extra para la perdida de grasa?, obviando dieta y cardio...Un saludo RASKOLNIKOV .

[Frutos111]

Entrenar pesado.

[raskolnikov]

En humanos esta demostrada su INEFICACIA como ayuda a la perdida de grasa.

¿Puedes poner el estudio o hacer referencia? no por que dude de tu palabra, pero es un tema que me interesa bastante. ¿Que recomiendas como ayuda extra para la perdida de grasa?, obviando dieta y cardio...Un saludo RASKOLNIKOV .

Estaban ya por el foro, en otro post de la L-carnitina pero no hay problema.

http://www.ncbi.nlm.nih.gov/pubmed/10861338
 

L-Carnitine supplementation combined with aerobic training does not promote weight loss in moderately obese women.
 
Villani RG, Gannon J, Self M, Rich PA.
 Source
 
Department of Human Biology and Movement Science, Royal Melbourne Institute of Technology, Melbourne, Victoria, 3083, Australia.
 
Abstract
 
L-Carnitine (L-C) transports fatty acids into mitochondria for oxidation and is marketed as a weight loss supplement. In a double-blind investigation to test the weight loss efficacy of L-C, 36 moderately overweight premenopausal women were pair matched on Body Mass Index (BMI) and randomly assigned to two groups (N = 18). For 8 weeks the L-C group ingested 2 g twice daily of L-C, while the placebo (P) group ingested the same amount of lactose. All subjects walked for 30 min (60-70% maximum heart rate) 4 days/week. Body composition, resting energy expenditure (REE) and substrate utilization were estimated before and after treatment. For the subjects who completed the study (15 P, 13 L-C), no significant changes in mean total body mass (TBM), fat mass FM, and resting lipid utilization occurred over time, nor were there any significant differences between groups for any variable. Conversely REE increased significantly for all subjects, but no between group differences existed. Five of the L-C group experienced nausea or diarrhea and consequently did not complete the study. Eight weeks of L-C ingestion and walking did not significantly alter the TBM or FM of overweight women, thereby casting doubt on the efficacy of L-C supplementation for weight loss.
 

Otro estudio en bipolares con sobrepeso asociado a la medicación, administró L-Carnitina durante 26 semanas. Se llamó "Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet" El título lo dice todo: absolutamente ineficaz.
 
http://www.ncbi.nlm.nih.gov/pubmed/17042889
 

Carnitine does not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet.

Elmslie JL, Porter RJ, Joyce PR, Hunt PJ, Mann JI.
 Source

Department of Psychological Medicine, Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand. jane.elmslie@chmeds.ac.nz
 
Abstract

OBJECTIVES:

Carnitine deficiency impairs fatty acid beta-oxidation and may partly explain weight gain in valproate-treated patients. The aim of this study was to determine whether l-carnitine supplementation improves weight loss outcomes in bipolar patients taking sodium valproate.
 METHODS:

Sixty bipolar patients with clinically significant weight gain thought to be related to sodium valproate, who had been taking sodium valproate for >or=6 months, were randomized to l-carnitine (15 mg/kg/day) or placebo for 26 weeks, in conjunction with a moderately energy-restricted, low-fat diet. The primary outcome measure was weight change.
 RESULTS:

l-carnitine had no effect on mean weight loss compared with placebo (-1.9 kg versus - 0.9 kg) (F = 0.778, df = 1,58, p = 0.381). The number of people in each group able to lose any weight was identical ( = 0, p = 1.0); more patients in the carnitine group (nine versus five) achieved a clinically significant weight loss (>or=5%) but this was not statistically significant (p = 1.0, Fisher's exact test).

 CONCLUSIONS:

At the dose prescribed in this study carnitine supplementation did not improve weight loss outcomes in valproate-treated bipolar patients consuming an energy-restricted, low-fat diet.
 

Otro estudio doble ciego durante 26 semanas administrando 2gr diarios a diabéticos no encontró ningún efecto. "The Effect of L-carnitine on plasma lipoprote in(a) Levels in Hyperchol esterolem ic Patients with Type 2 Diabetes Mellitus"
 
http://www.ncbi.nlm.nih.gov/pubmed/12867219
 

The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus.

Derosa G, Cicero AF, Gaddi A, Mugellini A, Ciccarelli L, Fogari R.
 Source

Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy. giuderosa@tin.it
 
Abstract

BACKGROUND:

A previous study has demonstrated that L-carnitine reduces plasma lipoprotein(a) (Lp[a]) levels in patients with hypercholesterolemia.
 OBJECTIVE:

To test a tolerable Lp(a)-reducing agent in diabetic patients, we assessed the effect of a dietary supplementation of L-carnitine on plasma lipid levels, particularly Lp(a), of patients with type 2 diabetes mellitus (DM) and hypercholesterolemia.
 METHODS:

In this 6-month, randomized, double-masked, placebo-controlled clinical trial, patients were enrolled, assessed, and followed up at the Diabetic and Metabolic Diseases Center of the Department of Internal Medicine and Therapeutics at the University of Pavia, Pavia, Italy. All study patients had newly diagnosed type 2 DM that was managed through dietary restriction alone throughout the study, as well as hypercholesterolemia. Patients were randomized to 1 of 2 groups. One group received L-carnitine, one 1-g tablet BID. The other group received a corresponding placebo. We assessed body mass index, fasting plasma glucose, postprandial plasma glucose, glycosylated hemoglobin, fasting plasma insulin, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein (apo) A-I, apo B, and Lp(a) at baseline and at 1, 3, and 6 months of treatment.
 RESULTS:

This study included 94 patients. The treatment group included 24 men and 22 women (mean [SD] age, 52 [6] years). The placebo group included 23 men and 25 women (mean [SD] age, 50 [7] years). The baseline characteristics of the groups did not differ significantly. The mean (SD) body weight, height, and body mass index were 78.2 (5.8) kg, 1.70 (0.04) m, and 27.3 (2.5) kg/m(2), respectively, in the L-carnitine group and 77.6 (6.4) kg, 1.71 (0.05) m, and 26.8 (2.2) kg/m(2), respectively, in the placebo group. In the treatment group, Lp(a) was significantly reduced at 3 and 6 months compared with baseline (P < 0.05) and P < 0.01, respectively). We observed a significant improvement after 6 months (P < 0.05) in the Lp(a) value in patients taking L-carnitine compared with those taking placebo. Between-group differences in other variables did not reach a level of significance at months 3 and 6. No drug-related adverse events were reported or observed.
 

CONCLUSION:
In this preliminary study, after 3 and 6 months, L-carnitine significantly lowered the plasma Lp(a) level compared with placebo in selected hypercholesterolemic patients with newly diagnosed type 2 DM.
 

Y para perder grasa, pues yohimbina.

[JordiBCN]

No tengo mucho que añadir la verdad. Básate en la dieta para perder peso.